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Isaac Guerendo

Pos: KR2, RB3 Team: SF YoE: 2
Draft: RD 4, PICK 129
Injury Status: H



I. Player News & Analysis


ESPN

RotoWire

Trends


"Guerendo, 24, is entering his second NFL season after playing a limited role off the bench for most of his rookie campaign. Granted, it was a small sample (99 touches), but the 2024 fourth-round pick was effective as both a rusher (5.0 YPC) and receiver (94% catch rate, 9.5 YPT). With Christian McCaffrey and Jordan Mason battling injuries, Guerendo played at least half the snaps in four games. In those weeks, he averaged 16.8 touches, 101.0 scrimmage yards and 17.9 fantasy points. The 49ers replaced Mason with Brian Robinson Jr. during the offseason, leaving Guerendo as a longshot to fantasy relevance. He'll only be worth adding should McCaffrey miss time and even then he may not be a starting option."


"As a rookie last season, Guerendo showcased some explosiveness out of the San Francisco backfield with averages of 5.0 yards per carry and 10.1 yards per reception over 16 games, but he has yet to play a snap on offense in the 49ers' first eight games of 2025. With lead back Christian McCaffrey having thus far stayed healthy while handling huge snap and touch counts each week, Brian Robinson has picked up the remaining scraps left over in the backfield. So long as McCaffrey and Robinson are able to avoid injury, Guerendo looks as though he'll be limited to a role on kickoff returns and kick-coverage units."

Isaac Guerendo's rushing yards per attempt has decreased by 75.0+% over the past 24 weeks.

Isaac Guerendo's rushing yards have decreased by 75.0+% over the past 24 weeks.

Isaac Guerendo's rushing attempt share has decreased by 75.0+% over the past 24 weeks.

Isaac Guerendo's rushing attempts have decreased by 75.0+% over the past 24 weeks.

Isaac Guerendo's targets have decreased by 66.67% over the past 26 weeks.


II. Historical Performance



Season

Week

Home

Score

Away

ATT

YD

TD

FUM

YPA

RUSH SHARE

2025

12

CAR

9 - 20

SF

0.0

0.0

0.0

0.0

0

0.0

2025

11

SF

41 - 22

ARI

0.0

0.0

0.0

0.0

0

0.0

2025

10

LAR

42 - 26

SF

0.0

0.0

0.0

0.0

0

0.0

2025

9

SF

34 - 24

NYG

0.0

0.0

0.0

0.0

0

0.0

2025

8

SF

15 - 26

HOU

0.0

0.0

0.0

0.0

0

0.0

2025

7

ATL

10 - 20

SF

0.0

0.0

0.0

0.0

0

0.0

2025

6

SF

19 - 30

TB

0.0

0.0

0.0

0.0

0

0.0

2025

5

SF

26 - 23

LAR

0.0

0.0

0.0

0.0

0

0.0

2025

4

JAX

26 - 21

SF

0.0

0.0

0.0

0.0

0

0.0

2025

3

ARI

15 - 16

SF

0.0

0.0

0.0

0.0

0

0.0

2025

2

SF

26 - 21

NO

0.0

0.0

0.0

0.0

0.0

0.0

2025

1

SF

17 - 13

SEA

0.0

0.0

0.0

0.0

0.0

0.0

2024

18

SF

24 - 47

ARI

2.0

5.0

0.0

0.0

2.5

0.071

2024

17

DET

40 - 34

SF

9.0

34.0

0.0

0.0

3.78

0.5

2024

15

LAR

12 - 6

SF

16.0

57.0

0.0

0.0

3.56

0.842

2024

14

CHI

13 - 38

SF

15.0

78.0

2.0

0.0

5.2

0.441

2024

13

SF

10 - 35

BUF

4.0

19.0

1.0

0.0

4.75

0.148

2024

12

SF

10 - 38

GB

0.0

0.0

0.0

0.0

0.0

0.0

2024

11

SEA

20 - 17

SF

0.0

0.0

0.0

0.0

0.0

0.0

2024

10

SF

23 - 20

TB

1.0

0.0

0.0

0.0

0.0

0.045

2024

8

DAL

24 - 30

SF

14.0

85.0

1.0

0.0

6.07

0.389

2024

7

KC

28 - 18

SF

1.0

2.0

0.0

0.0

2.0

0.042

2024

6

SF

36 - 24

SEA

10.0

99.0

0.0

0.0

9.9

0.303

2024

5

ARI

24 - 23

SF

5.0

22.0

0.0

0.0

4.4

0.192

2024

4

NE

13 - 30

SF

1.0

0.0

0.0

1.0

0.0

0.031

2024

3

SF

24 - 27

LAR

5.0

19.0

0.0

0.0

3.8

0.147

2024

2

SF

17 - 23

MIN

1.0

0.0

0.0

0.0

0.0

0.04

2024

1

NYJ

19 - 32

SF

0.0

0.0

0.0

0.0

0.0

0.0